Histone deacetylase inhibitor, CG200745 attenuates renal fibrosis in obstructive kidney disease

Tubulointerstitial fibrosis is a common feature of kidney disease. Histone deacetylase (HDAC) inhibitors have been reported to attenuate renal fibrosis progression. Here, we investigated the effect of CG200745, a novel HDAC inhibitor, on renal fibrosis development in a mouse model of unilateral uret...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Choi, Hong Sang, Song, Ji Hong, Kim, In Jin, Joo, Soo Yeon, Eom, Gwang Hyeon, Kim, Inkyeom, Cha, Hyunju, Cho, Joong Myung, Ma, Seong Kwon, Kim, Soo Wan, Bae, Eun Hui
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6070546/
https://ncbi.nlm.nih.gov/pubmed/30068917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30008-5
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