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CG200745, a Novel HDAC Inhibitor, Attenuates Kidney Fibrosis in a Murine Model of Alport Syndrome
Histone deacetylases have been a target of therapy for organ fibrosis. Here, we report the protective effect of CG200745 (CG), a novel histone deacetylase inhibitor, on tubulointerstitial fibrosis in Col4a3(−/−) mice, a murine model of Alport syndrome. Morphological analyses revealed CG treatment ma...
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| Veröffentlicht in: | Int J Mol Sci |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MDPI
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7073208/ https://ncbi.nlm.nih.gov/pubmed/32098220 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21041473 |
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