Histone deacetylase inhibitor, CG200745 attenuates renal fibrosis in obstructive kidney disease

Tubulointerstitial fibrosis is a common feature of kidney disease. Histone deacetylase (HDAC) inhibitors have been reported to attenuate renal fibrosis progression. Here, we investigated the effect of CG200745, a novel HDAC inhibitor, on renal fibrosis development in a mouse model of unilateral uret...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Choi, Hong Sang, Song, Ji Hong, Kim, In Jin, Joo, Soo Yeon, Eom, Gwang Hyeon, Kim, Inkyeom, Cha, Hyunju, Cho, Joong Myung, Ma, Seong Kwon, Kim, Soo Wan, Bae, Eun Hui
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6070546/
https://ncbi.nlm.nih.gov/pubmed/30068917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30008-5
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