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Histone deacetylase inhibitor, CG200745 attenuates renal fibrosis in obstructive kidney disease
Tubulointerstitial fibrosis is a common feature of kidney disease. Histone deacetylase (HDAC) inhibitors have been reported to attenuate renal fibrosis progression. Here, we investigated the effect of CG200745, a novel HDAC inhibitor, on renal fibrosis development in a mouse model of unilateral uret...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6070546/ https://ncbi.nlm.nih.gov/pubmed/30068917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30008-5 |
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