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Structural basis for selective inhibition of immunoglobulin E-receptor interactions by an anti-IgE antibody

Immunoglobulin E (IgE) antibodies play a central role in the allergic response: interaction with FcεRI on mast cells and basophils leads to immediate hypersensitivity reactions upon allergen challenge, while interaction with CD23/FcεRII, expressed on a variety of cells, regulates IgE synthesis among...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Chen, Jiun-Bo, Ramadani, Faruk, Pang, Marie O. Y., Beavil, Rebecca L., Holdom, Mary D., Mitropoulou, Alkistis N., Beavil, Andrew J., Gould, Hannah J., Chang, Tse Wen, Sutton, Brian J., McDonnell, James M., Davies, Anna M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6070508/
https://ncbi.nlm.nih.gov/pubmed/30069035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29664-4
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