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Structural basis for selective inhibition of immunoglobulin E-receptor interactions by an anti-IgE antibody
Immunoglobulin E (IgE) antibodies play a central role in the allergic response: interaction with FcεRI on mast cells and basophils leads to immediate hypersensitivity reactions upon allergen challenge, while interaction with CD23/FcεRII, expressed on a variety of cells, regulates IgE synthesis among...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6070508/ https://ncbi.nlm.nih.gov/pubmed/30069035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29664-4 |
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