Structural basis for selective inhibition of immunoglobulin E-receptor interactions by an anti-IgE antibody

Immunoglobulin E (IgE) antibodies play a central role in the allergic response: interaction with FcεRI on mast cells and basophils leads to immediate hypersensitivity reactions upon allergen challenge, while interaction with CD23/FcεRII, expressed on a variety of cells, regulates IgE synthesis among...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Chen, Jiun-Bo, Ramadani, Faruk, Pang, Marie O. Y., Beavil, Rebecca L., Holdom, Mary D., Mitropoulou, Alkistis N., Beavil, Andrew J., Gould, Hannah J., Chang, Tse Wen, Sutton, Brian J., McDonnell, James M., Davies, Anna M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2018
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6070508/
https://ncbi.nlm.nih.gov/pubmed/30069035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29664-4
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