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Dysregulation of NF-kB in glandular epithelial cells results in Sjögren’s-like features

The autoimmune disease primary Sjögren’s syndrome (pSS) is characterized by hypofunction of the salivary glands (SGs), the cause of which is not correlated to lymphocytic SG infiltration, as prevailing dogma often states. We knocked out the NF-κB proinflammatory pathway inhibitor A20 in keratin14(+)...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wang, Xiaoyan, Shaalan, Abeer, Liefers, Silvia, Coudenys, Julie, Elewaut, Dirk, Proctor, Gordon B., Bootsma, Hendrika, Kroese, Frans G. M., Pringle, Sarah
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6070175/
https://ncbi.nlm.nih.gov/pubmed/30067782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0200212
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