Dysregulation of NF-kB in glandular epithelial cells results in Sjögren’s-like features

The autoimmune disease primary Sjögren’s syndrome (pSS) is characterized by hypofunction of the salivary glands (SGs), the cause of which is not correlated to lymphocytic SG infiltration, as prevailing dogma often states. We knocked out the NF-κB proinflammatory pathway inhibitor A20 in keratin14(+)...

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Vydáno v:PLoS One
Hlavní autoři: Wang, Xiaoyan, Shaalan, Abeer, Liefers, Silvia, Coudenys, Julie, Elewaut, Dirk, Proctor, Gordon B., Bootsma, Hendrika, Kroese, Frans G. M., Pringle, Sarah
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6070175/
https://ncbi.nlm.nih.gov/pubmed/30067782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0200212
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