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Epithelial–immune cell interplay in primary Sjögren syndrome salivary gland pathogenesis

In primary Sjögren syndrome (pSS), the function of the salivary glands is often considerably reduced. Multiple innate immune pathways are likely dysregulated in the salivary gland epithelium in pSS, including the nuclear factor-κB pathway, the inflammasome and interferon signalling. The ductal cells...

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Détails bibliographiques
Publié dans:Nat Rev Rheumatol
Auteurs principaux: Verstappen, Gwenny M., Pringle, Sarah, Bootsma, Hendrika, Kroese, Frans G. M.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8081003/
https://ncbi.nlm.nih.gov/pubmed/33911236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41584-021-00605-2
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