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Epithelial–immune cell interplay in primary Sjögren syndrome salivary gland pathogenesis

In primary Sjögren syndrome (pSS), the function of the salivary glands is often considerably reduced. Multiple innate immune pathways are likely dysregulated in the salivary gland epithelium in pSS, including the nuclear factor-κB pathway, the inflammasome and interferon signalling. The ductal cells...

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Detalhes bibliográficos
Publicado no:Nat Rev Rheumatol
Main Authors: Verstappen, Gwenny M., Pringle, Sarah, Bootsma, Hendrika, Kroese, Frans G. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8081003/
https://ncbi.nlm.nih.gov/pubmed/33911236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41584-021-00605-2
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