Dysregulation of NF-kB in glandular epithelial cells results in Sjögren’s-like features

The autoimmune disease primary Sjögren’s syndrome (pSS) is characterized by hypofunction of the salivary glands (SGs), the cause of which is not correlated to lymphocytic SG infiltration, as prevailing dogma often states. We knocked out the NF-κB proinflammatory pathway inhibitor A20 in keratin14(+)...

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Pubblicato in:PLoS One
Autori principali: Wang, Xiaoyan, Shaalan, Abeer, Liefers, Silvia, Coudenys, Julie, Elewaut, Dirk, Proctor, Gordon B., Bootsma, Hendrika, Kroese, Frans G. M., Pringle, Sarah
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6070175/
https://ncbi.nlm.nih.gov/pubmed/30067782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0200212
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