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Klotho Inhibits Proliferation and Migration of Angiotensin II-Induced Vascular Smooth Muscle Cells (VSMCs) by Modulating NF-κB p65, Akt, and Extracellular Signal Regulated Kinase (ERK) Signaling Activities

BACKGROUND: It has been proven that phenotype shifting, from the contractile phenotype to the synthetic phenotype, of vascular smooth muscle cells (VSMCs), plays an important role in vascular diseases such as atherosclerosis, restenosis, and hypertension. Recently, accumulating evidence suggests tha...

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Bibliografiske detaljer
Udgivet i:Med Sci Monit
Main Authors: Yu, Shasha, Chen, Yintao, Chen, Shuang, Ye, Ning, Li, Yan, Sun, Yingxian
Format: Artigo
Sprog:Inglês
Udgivet: International Scientific Literature, Inc. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6069467/
https://ncbi.nlm.nih.gov/pubmed/30004089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.908038
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