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Atorvastatin Calcium Inhibits Phenotypic Modulation of PDGF-BB-Induced VSMCs via Down-Regulation the Akt Signaling Pathway

Plasticity of vascular smooth muscle cells (VSMCs) plays a central role in the onset and progression of proliferative vascular diseases. In adult tissue, VSMCs exist in a physiological contractile-quiescent phenotype, which is defined by lack of the ability of proliferation and migration, while high...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Chen, Shuang, Liu, Baoqin, Kong, Dehui, Li, Si, Li, Chao, Wang, Huaqin, Sun, Yingxian
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398430/
https://ncbi.nlm.nih.gov/pubmed/25874930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122577
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