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Klotho Inhibits Proliferation and Migration of Angiotensin II-Induced Vascular Smooth Muscle Cells (VSMCs) by Modulating NF-κB p65, Akt, and Extracellular Signal Regulated Kinase (ERK) Signaling Activities

BACKGROUND: It has been proven that phenotype shifting, from the contractile phenotype to the synthetic phenotype, of vascular smooth muscle cells (VSMCs), plays an important role in vascular diseases such as atherosclerosis, restenosis, and hypertension. Recently, accumulating evidence suggests tha...

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Detalhes bibliográficos
Publicado no:Med Sci Monit
Main Authors: Yu, Shasha, Chen, Yintao, Chen, Shuang, Ye, Ning, Li, Yan, Sun, Yingxian
Formato: Artigo
Idioma:Inglês
Publicado em: International Scientific Literature, Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6069467/
https://ncbi.nlm.nih.gov/pubmed/30004089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.908038
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