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Angiotensin-(1–7) abrogates angiotensin II-induced proliferation, migration and inflammation in VSMCs through inactivation of ROS-mediated PI3K/Akt and MAPK/ERK signaling pathways

The proliferation, migration and inflammation of vascular smooth muscle cells (VSMCs) contribute to the pathogenesis and progression of several cardiovascular diseases such as atherosclerosis and hypertension. Angiotensin (Ang)-(1–7) and Ang II are identified to be involved in regulating cardiovascu...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Feng, Ren, Xingsheng, Zhao, Mingxia, Zhou, Bing, Han, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5043354/
https://ncbi.nlm.nih.gov/pubmed/27687768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34621
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