Angiotensin-(1–7) abrogates angiotensin II-induced proliferation, migration and inflammation in VSMCs through inactivation of ROS-mediated PI3K/Akt and MAPK/ERK signaling pathways

The proliferation, migration and inflammation of vascular smooth muscle cells (VSMCs) contribute to the pathogenesis and progression of several cardiovascular diseases such as atherosclerosis and hypertension. Angiotensin (Ang)-(1–7) and Ang II are identified to be involved in regulating cardiovascu...

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Udgivet i:Sci Rep
Main Authors: Zhang, Feng, Ren, Xingsheng, Zhao, Mingxia, Zhou, Bing, Han, Ying
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5043354/
https://ncbi.nlm.nih.gov/pubmed/27687768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34621
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