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Apelin induces the proliferation, migration and expression of cytoskeleton and tight junction proteins in human RPE cells via PI-3K/Akt and MAPK/Erk signaling pathways
Diabetic retinopathy is major cause of vision loss during working age. Breakdown of blood-retinal barrier is an early event in pathogenesis of DR. RPE is the major part of outer BRB. Apelin, an endogenous ligand of APJ, mediates angiogenesis. Our previous study showed that apelin induced proliferati...
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| Published in: | Int J Clin Exp Pathol |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
e-Century Publishing Corporation
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6965848/ https://ncbi.nlm.nih.gov/pubmed/31966415 |
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