Apelin attenuates the osteoblastic differentiation of aortic valve interstitial cells via the ERK and PI3-K/Akt pathways

Aortic valve calcification (AVC), which used to be recognized as a passive and irreversible process, is now widely accepted as an active and regulated process characterized by osteoblastic differentiation of aortic valve interstitial cells (AVICs). Apelin, the endogenous ligand for G-protein-coupled...

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Detalhes bibliográficos
Publicado no:Amino Acids
Main Authors: Yuan, Zhao-shun, Zhou, Yang-zhao, Liao, Xiao-bo, Luo, Jia-wen, Shen, Kang-jun, Hu, Ye-rong, Gu, Lu, Li, Jian-ming, Tan, Chang-ming, Chen, He-ming, Zhou, Xin-min
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Vienna 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633450/
https://ncbi.nlm.nih.gov/pubmed/26142632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00726-015-2020-3
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