Apelin-13 Is an Early Promoter of Cytoskeleton and Tight Junction in Diabetic Macular Edema via PI-3K/Akt and MAPK/Erk Signaling Pathways

Diabetic macular edema is major cause of vision loss associated with diabetic retinopathy. Breakdown of blood-retinal barrier, especially inner BRB, is an early event in pathogenesis of DR. Apelin, an endogenous ligand of APJ, mediates angiogenesis and is involved in the development of DR. The prese...

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Gepubliceerd in:Biomed Res Int
Hoofdauteurs: Li, Yang, Bai, Yu-jing, Jiang, Yan-rong, Yu, Wen-zhen, Shi, Xuan, Chen, Li, Feng, Jing, Sun, Gui-bo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Hindawi 2018
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5904819/
https://ncbi.nlm.nih.gov/pubmed/29850504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/3242574
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