Klotho Inhibits Proliferation and Migration of Angiotensin II-Induced Vascular Smooth Muscle Cells (VSMCs) by Modulating NF-κB p65, Akt, and Extracellular Signal Regulated Kinase (ERK) Signaling Activities

BACKGROUND: It has been proven that phenotype shifting, from the contractile phenotype to the synthetic phenotype, of vascular smooth muscle cells (VSMCs), plays an important role in vascular diseases such as atherosclerosis, restenosis, and hypertension. Recently, accumulating evidence suggests tha...

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Vydáno v:Med Sci Monit
Hlavní autoři: Yu, Shasha, Chen, Yintao, Chen, Shuang, Ye, Ning, Li, Yan, Sun, Yingxian
Médium: Artigo
Jazyk:Inglês
Vydáno: International Scientific Literature, Inc. 2018
Témata:
Lab/In Vitro Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6069467/
https://ncbi.nlm.nih.gov/pubmed/30004089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.908038
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