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A Fast Approximate Algorithm for Mapping Long Reads to Large Reference Databases

Emerging single-molecule sequencing technologies from Pacific Biosciences and Oxford Nanopore have revived interest in long-read mapping algorithms. Alignment-based seed-and-extend methods demonstrate good accuracy, but face limited scalability, while faster alignment-free methods typically trade de...

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Detalhes bibliográficos
Publicado no:J Comput Biol
Main Authors: Jain, Chirag, Dilthey, Alexander, Koren, Sergey, Aluru, Srinivas, Phillippy, Adam M.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6067103/
https://ncbi.nlm.nih.gov/pubmed/29708767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2018.0036
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