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Fast and accurate read mapping with approximate seeds and multiple backtracking

We present Masai, a read mapper representing the state-of-the-art in terms of speed and accuracy. Our tool is an order of magnitude faster than RazerS 3 and mrFAST, 2–4 times faster and more accurate than Bowtie 2 and BWA. The novelties of our read mapper are filtration with approximate seeds and a...

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Detalhes bibliográficos
Main Authors: Siragusa, Enrico, Weese, David, Reinert, Knut
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627565/
https://ncbi.nlm.nih.gov/pubmed/23358824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt005
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