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A novel and well-defined benchmarking method for second generation read mapping

BACKGROUND: Second generation sequencing technologies yield DNA sequence data at ultra high-throughput. Common to most biological applications is a mapping of the reads to an almost identical or highly similar reference genome. The assessment of the quality of read mapping results is not straightfor...

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Detalhes bibliográficos
Main Authors: Holtgrewe, Manuel, Emde, Anne-Katrin, Weese, David, Reinert, Knut
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128034/
https://ncbi.nlm.nih.gov/pubmed/21615913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-210
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