A consistency-based consensus algorithm for de novo and reference-guided sequence assembly of short reads

Motivation: Novel high-throughput sequencing technologies pose new algorithmic challenges in handling massive amounts of short-read, high-coverage data. A robust and versatile consensus tool is of particular interest for such data since a sound multi-read alignment is a prerequisite for variation an...

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Bibliographic Details
Main Authors: Rausch, Tobias, Koren, Sergey, Denisov, Gennady, Weese, David, Emde, Anne-Katrin, Döring, Andreas, Reinert, Knut
Format: Artigo
Language:Inglês
Published: Oxford University Press 2009
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Original Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732307/
https://ncbi.nlm.nih.gov/pubmed/19269990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btp131
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