Mitochondrial Pharmacology of Dimebon (Latrepirdine) Calls for a New Look at its Possible Therapeutic Potential in Alzheimer’s Disease

Dimebon (latrepirdine), an old antihistaminic drug, showed divergent results in two large clinical trials in Alzheimer disease (AD), which according to our review might be related to the specific pharmacological properties of the drug and the different patient populations included in both studies. O...

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Bibliographic Details
Published in:Aging Dis
Main Authors: Eckert, Schamim H, Gaca, Janett, Kolesova, Nathalie, Friedland, Kristina, Eckert, Gunter P, Muller, Walter E
Format: Artigo
Language:Inglês
Published: JKL International LLC 2018
Subjects:
Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6065284/
https://ncbi.nlm.nih.gov/pubmed/30090660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14336/AD.2017.1014
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