The Calcium-Dependent Protease Calpain-1 Links TRPC6 Activity to Podocyte Injury

BACKGROUND: The hallmark of podocytopathies, such as FSGS, is podocyte injury resulting in proteinuria. Transient receptor potential channel C6 (TRPC6) is a calcium-conducting ion channel expressed at the slit diaphragm. TRPC6 gain-of-function mutations and glomerular TRPC6 overexpression are associ...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Verheijden, Kim A.T., Sonneveld, Ramon, Bakker-van Bebber, Marinka, Wetzels, Jack F.M., van der Vlag, Johan, Nijenhuis, Tom
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2018
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6065075/
https://ncbi.nlm.nih.gov/pubmed/29954830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016111248
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados