Ligation of α-Dystroglycan on Podocytes Induces Intracellular Signaling: A New Mechanism for Podocyte Effacement?

BACKGROUND: α-Dystroglycan is a negatively charged glycoprotein that covers the apical and basolateral membrane of the podocyte. Its transmembrane binding to the cytoskeleton is regulated via tyrosine phosphorylation (pY892) of β-dystroglycan. At the basolateral side α-dystroglycan binds the glomeru...

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Main Authors: Vogtländer, Nils P. J., Visch, Henk Jan, Bakker, Marinka A. H., Berden, Jo H. M., van der Vlag, Johan
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2009
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695560/
https://ncbi.nlm.nih.gov/pubmed/19543532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005979
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