Prenatal caffeine exposure-induced adrenal developmental abnormality in male offspring rats and its possible intrauterine programming mechanisms

Glucocorticoid (GC) is a major factor for fetal tissue maturation and fate decision after birth. We previously demonstrated that prenatal caffeine exposure (PCE) suppressed fetal adrenal steroidogenesis and resulted in adrenal dysplasia. However, whether these changes play a role until adulthood and...

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Dettagli Bibliografici
Pubblicato in:Toxicol Res (Camb)
Autori principali: He, Zheng, Zhu, Chunyan, Huang, Hegui, Liu, Lian, Wang, Linlong, Chen, Liaobin, Magdalou, Jacques, Wang, Hui
Natura: Artigo
Lingua:Inglês
Pubblicazione: Royal Society of Chemistry 2016
Soggetti:
Chemistry
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6060702/
https://ncbi.nlm.nih.gov/pubmed/30090354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5tx00265f
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