Prenatal caffeine exposure-induced adrenal developmental abnormality in male offspring rats and its possible intrauterine programming mechanisms

Glucocorticoid (GC) is a major factor for fetal tissue maturation and fate decision after birth. We previously demonstrated that prenatal caffeine exposure (PCE) suppressed fetal adrenal steroidogenesis and resulted in adrenal dysplasia. However, whether these changes play a role until adulthood and...

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Veröffentlicht in:Toxicol Res (Camb)
Hauptverfasser: He, Zheng, Zhu, Chunyan, Huang, Hegui, Liu, Lian, Wang, Linlong, Chen, Liaobin, Magdalou, Jacques, Wang, Hui
Format: Artigo
Sprache:Inglês
Veröffentlicht: Royal Society of Chemistry 2016
Schlagworte:
Chemistry
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6060702/
https://ncbi.nlm.nih.gov/pubmed/30090354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5tx00265f
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