The low‐expression programming of 11β‐HSD2 mediates osteoporosis susceptibility induced by prenatal caffeine exposure in male offspring rats

BACKGROUND AND PURPOSE: Prenatal caffeine exposure (PCE) can cause developmental toxicity of long bones in offspring, but the long‐term effects and the underlying mechanism have not been fully clarified. Here, we investigated the effects of PCE peak bone mass accumulation and osteoporosis susceptibi...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Xiao, Hao, Wu, Zhixin, Li, Bin, Shangguan, Yangfan, Stoltz, Jean‐François, Magdalou, Jacques, Chen, Liaobin, Wang, Hui
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7520449/
https://ncbi.nlm.nih.gov/pubmed/32757222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.15225
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