Prenatal caffeine exposure induces a poor quality of articular cartilage in male adult offspring rats via cholesterol accumulation in cartilage

Epidemiological investigations indicate that osteoarthritis is associated with intrauterine growth retardation (IUGR) and abnormal cholesterol metabolism. Our previous studies showed that prenatal caffeine exposure (PCE) induced chondrogenesis retardation in IUGR offspring rats. The current study so...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Luo, Hanwen, Li, Jing, Cao, Hong, Tan, Yang, Magdalou, Jacques, Chen, Liaobin, Wang, Hui
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671025/
https://ncbi.nlm.nih.gov/pubmed/26639318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17746
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