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The low‐expression programming of 11β‐HSD2 mediates osteoporosis susceptibility induced by prenatal caffeine exposure in male offspring rats

BACKGROUND AND PURPOSE: Prenatal caffeine exposure (PCE) can cause developmental toxicity of long bones in offspring, but the long‐term effects and the underlying mechanism have not been fully clarified. Here, we investigated the effects of PCE peak bone mass accumulation and osteoporosis susceptibi...

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Publicat a:Br J Pharmacol
Autors principals: Xiao, Hao, Wu, Zhixin, Li, Bin, Shangguan, Yangfan, Stoltz, Jean‐François, Magdalou, Jacques, Chen, Liaobin, Wang, Hui
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7520449/
https://ncbi.nlm.nih.gov/pubmed/32757222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.15225
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