Intrauterine programming of cartilaginous 11β-HSD2 induced by corticosterone and caffeine mediated susceptibility to adult osteoarthritis

Our previous study reported that prenatal caffeine exposure (PCE) could induce chondrodysplasia and increase the susceptibility to osteoarthritis in offspring rats. However, the potential mechanisms and initiating factors remain unknown. This study aims to investigate whether 11β-HSD2, a glucocortic...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Huasong Shi, Bin Li, Hui Gao, Hangyuan He, Zhixin Wu, Jacques Magdaloud, Hui Wang, Liaobin Chen
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2022-07-01
Colecção:Ecotoxicology and Environmental Safety
Assuntos:
Osteoarthritis
Prenatal caffeine exposure
Intrauterine programming
Glucocorticoid
11β-HSD2
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S014765132200464X
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados