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UDP-glucose dehydrogenase modulates proteoglycan synthesis in articular chondrocytes: its possible involvement and regulation in osteoarthritis

INTRODUCTION: The objective of this study was to investigate the possible role of UDP-glucose dehydrogenase (UGDH) in osteoarthritis (OA) and uncover whether, furthermore how interleukin-1beta (IL-1β) affects UGDH gene expression. METHODS: UGDH specific siRNAs were applied to determine the role of U...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Wen, Yinxian, Li, Jing, Wang, Linlong, Tie, Kai, Magdalou, Jacques, Chen, Liaobin, Wang, Hui
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298080/
https://ncbi.nlm.nih.gov/pubmed/25465897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-014-0484-2
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