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UDP-glucose dehydrogenase modulates proteoglycan synthesis in articular chondrocytes: its possible involvement and regulation in osteoarthritis
INTRODUCTION: The objective of this study was to investigate the possible role of UDP-glucose dehydrogenase (UGDH) in osteoarthritis (OA) and uncover whether, furthermore how interleukin-1beta (IL-1β) affects UGDH gene expression. METHODS: UGDH specific siRNAs were applied to determine the role of U...
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| Publicado no: | Arthritis Res Ther |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4298080/ https://ncbi.nlm.nih.gov/pubmed/25465897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-014-0484-2 |
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