Angelica Sinensis Polysaccharides Stimulated UDP-Sugar Synthase Genes through Promoting Gene Expression of IGF-1 and IGF1R in Chondrocytes: Promoting Anti-Osteoarthritic Activity

BACKGROUND: Osteoarthritis (OA) is a chronic joints disease characterized by progressive degeneration of articular cartilage due to the loss of cartilage matrix. Previously, we found, for the first time, that an acidic glycan from Angelica Sinensis Polysaccharides (APSs), namely the APS-3c, could pr...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wen, Yinxian, Li, Jing, Tan, Yang, Qin, Jun, Xie, Xianfei, Wang, Linlong, Mei, Qibing, Wang, Hui, Magdalou, Jacques, Chen, Liaobin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2014
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159308/
https://ncbi.nlm.nih.gov/pubmed/25202993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107024
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