Angelica Sinensis Polysaccharides Stimulated UDP-Sugar Synthase Genes through Promoting Gene Expression of IGF-1 and IGF1R in Chondrocytes: Promoting Anti-Osteoarthritic Activity

BACKGROUND: Osteoarthritis (OA) is a chronic joints disease characterized by progressive degeneration of articular cartilage due to the loss of cartilage matrix. Previously, we found, for the first time, that an acidic glycan from Angelica Sinensis Polysaccharides (APSs), namely the APS-3c, could pr...

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Detaylı Bibliyografya
Asıl Yazarlar: Wen, Yinxian, Li, Jing, Tan, Yang, Qin, Jun, Xie, Xianfei, Wang, Linlong, Mei, Qibing, Wang, Hui, Magdalou, Jacques, Chen, Liaobin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2014
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159308/
https://ncbi.nlm.nih.gov/pubmed/25202993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107024
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