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Novel Key Players in the Development of Tau Neuropathology: Focus on the 5-Lipoxygenase

Tauopathies belong to a large group of neurodegenerative diseases characterized by progressive accumulation of hyperphosphorylated tau. Tau is a microtubule binding protein which is necessary for their assembly and stability. However, tau affinity for microtubules mainly depends on its phosphorylati...

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Dettagli Bibliografici
Pubblicato in:J Alzheimers Dis
Autori principali: Lauretti, Elisabetta, Praticò, Domenico
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6058721/
https://ncbi.nlm.nih.gov/pubmed/29758943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-179931
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