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Knockout of 5-lipoxygenase prevents dexamethasone-induced tau pathology in 3xTg mice
Emerging evidence suggests that dysregulation stress hormones, such as glucocorticoids, in aged persons put them at a higher risk to develop Alzheimer’s disease (AD). However, the mechanisms underlying such vulnerability remain to be unraveled. Pharmacologic inhibition of 5-lipoxygenase (5LO), an ac...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3714329/ https://ncbi.nlm.nih.gov/pubmed/23634895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12096 |
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