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The 12-15Lipoxygenase is a modulator of Alzheimer’s related tau pathology in vivo
12/15-Lipoxygenase (12/15LO) is a lipid-peroxidizing enzyme widely expressed in the central nervous system where it has been involved in the neurobiology of Alzheimer disease (AD) because it modulates Amyloid beta (Aβ) and APP processing. However, its biological effect on tau protein is unknown. We...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3838477/ https://ncbi.nlm.nih.gov/pubmed/23862663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12136 |
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