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The 12-15Lipoxygenase is a modulator of Alzheimer’s related tau pathology in vivo

12/15-Lipoxygenase (12/15LO) is a lipid-peroxidizing enzyme widely expressed in the central nervous system where it has been involved in the neurobiology of Alzheimer disease (AD) because it modulates Amyloid beta (Aβ) and APP processing. However, its biological effect on tau protein is unknown. We...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Giannopoulos, Phillip F., Joshi, Yash B., Chu, Jin, Praticò, Domenico
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838477/
https://ncbi.nlm.nih.gov/pubmed/23862663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12136
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