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The 5-Lipoxygenase as modulator of Alzheimer’s γ-secretase and therapeutic target
Alzheimer’s disease (AD) is an age-related, neurodegenerative disorder characterized by cognitive impairment with memory loss, extracellular amyloid beta (Aβ) peptides aggregation, and intracellular hyper-phosphorylated tau neurofibrillary tangles (NFT) accumulation. Although the 5-lipoxygenase (5LO...
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| Gepubliceerd in: | Brain Res Bull |
|---|---|
| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5028246/ https://ncbi.nlm.nih.gov/pubmed/27005438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainresbull.2016.03.010 |
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