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Alzheimer’s disease: phenotypic approaches using disease models and the targeting of tau protein

INTRODUCTION: Hyperphosphorylated and aggregated tau protein is the main hallmark of a class of neurodegenerative disorders known as tauopathies. Tau is a microtubule binding protein which is important for microtubule assembly and stabilization, for proper axonal transport and overall neuronal integ...

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Detalhes bibliográficos
Publicado no:Expert Opin Ther Targets
Main Authors: Lauretti, Elisabetta, Praticò, Domenico
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7201870/
https://ncbi.nlm.nih.gov/pubmed/32116063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14728222.2020.1737012
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