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Glucose deprivation increases tau phosphorylation via P38 mitogen‐activated protein kinase

Alterations of glucose metabolism have been observed in Alzheimer's disease (AD) brain. Previous studies showed that glucose deprivation increases amyloidogenesis via a BACE‐1‐dependent mechanism. However, no data are available on the effect that this condition may have on tau phosphorylation....

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Bibliografiske detaljer
Udgivet i:Aging Cell
Main Authors: Lauretti, Elisabetta, Praticò, Domenico
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4693472/
https://ncbi.nlm.nih.gov/pubmed/26219917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12381
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