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Alzheimer’s disease: phenotypic approaches using disease models and the targeting of tau protein
INTRODUCTION: Hyperphosphorylated and aggregated tau protein is the main hallmark of a class of neurodegenerative disorders known as tauopathies. Tau is a microtubule binding protein which is important for microtubule assembly and stabilization, for proper axonal transport and overall neuronal integ...
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| 出版年: | Expert Opin Ther Targets |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2020
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7201870/ https://ncbi.nlm.nih.gov/pubmed/32116063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14728222.2020.1737012 |
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