Patient HLA class I genotype influences cancer response to checkpoint blockade immunotherapy

CD8(+) T cell–dependent killing of cancer cells requires efficient presentation of tumor antigens by human leukocyte antigen class I (HLA-I) molecules. However, the extent to which patient-specific HLA-I genotype influences response to anti–programmed cell death protein 1 or anti–cytotoxic T lymphoc...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Science
Main Authors: Chowell, Diego, Morris, Luc G. T., Grigg, Claud M., Weber, Jeffrey K., Samstein, Robert M., Makarov, Vladimir, Kuo, Fengshen, Kendall, Sviatoslav M., Requena, David, Riaz, Nadeem, Greenbaum, Benjamin, Carroll, James, Garon, Edward, Hyman, David M., Zehir, Ahmet, Solit, David, Berger, Michael, Zhou, Ruhong, Rizvi, Naiyer A., Chan, Timothy A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6057471/
https://ncbi.nlm.nih.gov/pubmed/29217585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aao4572
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados