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Metabolic reprogramming enables hepatocarcinoma cells to efficiently adapt and survive to a nutrient-restricted microenvironment

Hepatocellular carcinoma (HCC) is a metabolically heterogeneous cancer and the use of glucose by HCC cells could impact their tumorigenicity. Dt81Hepa1-6 cells display enhanced tumorigenicity compared to parental Hepa1-6 cells. This increased tumorigenicity could be explained by a metabolic adaptati...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Cassim, Shamir, Raymond, Valérie-Ann, Dehbidi-Assadzadeh, Layla, Lapierre, Pascal, Bilodeau, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6056217/
https://ncbi.nlm.nih.gov/pubmed/29633904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2018.1460023
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