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From in vivo to in vitro: Major metabolic alterations take place in hepatocytes during and following isolation

The liver plays a key role in maintaining physiological homeostasis and hepatocytes are largely responsible for this. The use of isolated primary hepatocytes has become an essential tool for the study of nutrient physiology, xenobiotic metabolism and several liver pathologies. Since hepatocytes are...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Cassim, Shamir, Raymond, Valérie-Ann, Lapierre, Pascal, Bilodeau, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746264/
https://ncbi.nlm.nih.gov/pubmed/29284039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0190366
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