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Highly tumorigenic hepatocellular carcinoma cell line with cancer stem cell-like properties

There are limited numbers of models to study hepatocellular carcinoma (HCC) in vivo in immunocompetent hosts. In an effort to develop a cell line with improved tumorigenicity, we derived a new cell line from Hepa1-6 cells through an in vivo passage in C57BL/6 mice. The resulting Dt81Hepa1-6 cell lin...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lacoste, Benoit, Raymond, Valérie-Ann, Cassim, Shamir, Lapierre, Pascal, Bilodeau, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5289561/
https://ncbi.nlm.nih.gov/pubmed/28152020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171215
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