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Metabolite profiling identifies a signature of tumorigenicity in hepatocellular carcinoma

HCC (Hepatocellular carcinoma) cells exhibit greater metabolic plasticity than normal hepatocytes since they must survive in a dynamic microenvironment where nutrients and oxygen are often scarce. Using a metabolomic approach combined with functional in vitro and in vivo assays, we aimed to identify...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Cassim, Shamir, Raymond, Valérie-Ann, Lacoste, Benoit, Lapierre, Pascal, Bilodeau, Marc
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003570/
https://ncbi.nlm.nih.gov/pubmed/29928490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25525
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