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Translational Reprogramming Marks Adaptation to Asparagine Restriction in Cancer
While amino acid restriction remains an attractive strategy for cancer therapy, metabolic adaptations limit its effectiveness. Here we demonstrate a role of translational reprogramming in the survival of asparagine-restricted cancer cells. Asparagine limitation in melanoma and pancreatic cancer cell...
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| Publicado no: | Nat Cell Biol |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7307327/ https://ncbi.nlm.nih.gov/pubmed/31740775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-019-0415-1 |
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