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A toxic imbalance of Hsp70s in Saccharomyces cerevisiae is caused by competition for cofactors

Molecular chaperones are responsible for managing protein folding from translation through degradation. These crucial machines ensure that protein homeostasis is optimally maintained for cell health. However, “too much of a good thing” can be deadly, and the excess of chaperones can be toxic under c...

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Dades bibliogràfiques
Publicat a:Mol Microbiol
Autors principals: Keefer, Kathryn M., True, Heather L.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054465/
https://ncbi.nlm.nih.gov/pubmed/28665048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13741
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