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A toxic imbalance of Hsp70s in Saccharomyces cerevisiae is caused by competition for cofactors

Molecular chaperones are responsible for managing protein folding from translation through degradation. These crucial machines ensure that protein homeostasis is optimally maintained for cell health. However, “too much of a good thing” can be deadly, and the excess of chaperones can be toxic under c...

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Detalhes bibliográficos
Publicado no:Mol Microbiol
Main Authors: Keefer, Kathryn M., True, Heather L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054465/
https://ncbi.nlm.nih.gov/pubmed/28665048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13741
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